Cyclopyrrolones
(Wiki)
Cyclopyrrolones are a family of sedating and tranquilising drugs and are, whilst chemically unrelated to Benzodiazepines, still function via the
Benzodiazepine/GABA neurotransmitter.
Pagoclone
(Wiki)
Brand names:
None known
Formula: C23H22ClN3O2
Half life: Unknown
Single unit dose: Unknown
Recommended outpatient dose: Unknown
Maximum outpatient dose: Unknown
Although
related to the drug Zopiclone, Pagoclone exhibits tranquilising effects rather than sedation. Interestingly, David Nutt of
Bristol University, UK,
has suggested that Pagoclone could be used as a recreational drug as it exhibits the pleasant benefits
of alcohol (relaxation, sociability) wihtout many of the down sides (such
as aggression, amnesia and liver damage). It's effects can be reversed by a
dose of Flumazenil, a drug that is often used as an
antidote to Benzodiazepines overdose. Pagoclone is being trialed as a
drug to improve stammerer's
speech fluency. At the present time
the drug is not licenced.
Pazinaclone
(Wiki)
Brand names:
None known
Formula: C25H23ClN4O4
Half life: ~ 6 hours
Single unit dose: Unknown
Recommended outpatient dose: Unknown
Maximum outpatient dose: Unknown
Whilst
mainly a tranquiliser, at higher doses, Pazinaclone functions as a sedative.
Suproclone
(Wiki)
Brand names:
Lunesta®
Formula: C22H22ClN5O4S2
Half life: ~ 6 hours
Single unit dose: Unknown
Recommended outpatient dose: Unkown
Maximum outpatient dose: 6mg Uknown
Whilst
mainly a tranquiliser, at higher doses, Suproclone functions as a sedative.
Suriclone
(Wiki)
Brand names:
Suril®
Formula: C20H20ClN5O3S2
Half life: Unknwon
Single unit dose: Unknown
Recommended outpatient dose: Unknown
Maximum outpatient dose: Unknown
Whilst
mainly a tranquiliser, at higher doses, Suriclone functions as a sedative. It is structurally unrelated
to Benzodiazepines.