Diphenylbutylpiperidines
(Wiki)
A chemical subset defining a type or
family of Typical Antipsychotic drugs.
Fluspirilene
(Wiki)
Brand names:
None known
Formula: C29H31F2N3O
Half life: Unknown
Single unit dose: Unknown
Recommended outpatient dose: 13mg per day
[Not
Verified]
Maximum outpatient dose: 20mg per day
[Not
Verified]
A
Typical Antipsychotic drug that is administered
intramuscularly.
Penfluridol
(Wiki)
Brand names:
Micefal®, Semap®
Formula: C28H27ClF5NO
Half life: 66 hours
Single unit dose: Unknown
Recommended outpatient dose: Unknown
Maximum outpatient dose: Unknown
A highly potent,
first generation Diphenylbutylpiperidine
Typical Antipsychotic, Penfluridol was discovered in 1986.
Penfluridol has a particularly long
elimination half life and as such will remain in the system
for many days after administration. It is mildly
sedative but unfortuantely has a high
side effect profile, potentially causing
Akathisia, Dyskinesiae and pseudo-Parkinsonism.
Pimozide
(Wiki)
Brand names:
Orap®
Formula: C28H29F2N3O
Half life: ~ 55 hours
Single unit dose: Unknown
Recommended outpatient dose: 6mg per day
[Verified]
Maximum outpatient dose: 20mg per day
[Verified]
This
drug truly is the treatment of last resort; it is only ever used
when all other major avenues of treatment have been exhausted. The
drug is thought to be carcinogenic and has a high incidence rate
of tardive dyskinesia, neuroleptic malignant
syndrome, akathisia and long QT syndrome. The medication appears to be generally a
stimulant and is to be administered with great
care to patients, no matter what. It is not suggested
that this drug be prescribed to depressed individuals since it frequently
causes depression in neutral patients, often so much so that
suicidal behaviour develops.