Butyrophenones (Wiki)

Butyrophenones are psychiatric drugs aimed primarily at the treatment of psychotic illnesses.


Benperidol (Wiki)

Brand names: Anquil®, Benquil®
Formula: C22H24FN3O2
Half life: Unknown
Single unit dose: Unknown
Recommended outpatient dose: 0.25mg per day [Verified]
Maximum outpatient dose: 1.5mg per day [Verified]

Benperidol is the most potent neuroleptic drug available on the European market and is primarily used in the treatment of antisocial hypersexual behaviour, but can be applied to psychotic illnesses.

Droperidol (Wiki)

Brand names: Dropletan®, Inapsine®
Formula: C22H22FN3O2
Half life: ~ 2 hours
Single unit dose: Unknown
Recommended outpatient dose: 2.5mg per day [Not Verified]
Maximum outpatient dose: 5mg per day [Highly Questionable]

Also used in the treatment of postoperative nausea and/or vomiting at low doses (up to 1.25mg per day), droperidol is typically sedative.

Haloperidol (Wiki)

Brand names: Aloperidin®, Bioperidolo®, Brotopon®, Dozic®, Einalon S®, Eukystol®, Haldol®, Halosten®, Keselan®, Linton®, Peluces®, Serenace®, Serenase®, Sigaperidol®
Formula: C21H23ClFNO2
Half life: ~ 21 hours
Single unit dose: 2mg per day
Recommended outpatient dose: 10mg per day [Not Verified]
Maximum outpatient dose: 100mg per day [Verified]

Developed in 1957, haloperidol became a preferred drug in medical circles and is still used today, albeit as a backup medication.

Haloperidol is especially effective against positive psychotic symptoms, such as hallucinations and delusions; modern antipsychotics remain less effective than this drug in this field. It is fairly sedative and tranquilising, making it a good drug to be administered to agitated or manic patients.

Although it is an old and largely superseded medication, it is still regarded with respect and is often used as an emergency drug, to be used in minor crises. As a treatment, it has been demoted from the front line, mostly due to a high incidence rate of side effects; for instance, this drug is, alongside fluphenazine, the most likely therapeutic drug to cause neuroleptic malignant syndrome (NMS).

Melperone (Wiki)

Brand names: Buronil®, Burnil®, Eunerpan®
Formula: C16H23ClFNO
Half life: Unknown
Single unit dose: Unknown
Recommended outpatient dose: Unknown
Maximum outpatient dose: Unknown

No current data.

Triperidol (Wiki)

Brand names: None known
Formula: C22H23F4NO2
Half life: Unknown
Single unit dose: Unknown
Recommended outpatient dose: Unknown
Maximum outpatient dose: Unknown

No current data.