Dec 2007

Efficacy of antidepressants

According to:

S. Rambelomanana, F. Depont, K. Forest, G. Hébert, S. Blazejewski, A. Fourrier-Réglat, M. Molimard, N. Moore (2006)
Antidepressants: general practitioners’ opinions and clinical practice
Acta Psychiatrica Scandinavica 113 (6), 460–467:


Antidepressants most often stopped for lack of efficacy were Fluvoxamine (28.6%), Moclobemide (28.6%), Clomipramine (25%), and Tianeptine (24.4%).

Antidepressants found to be most effective are Paroxetine (87.4% good or very good tolerability), Fluoxetine (85.4%), and Tianeptine (82.7%).